Villa Stiassni was built in 1927–1929 according to the design of the famous Brno architect Ernst Wiesner for the family of the Jewish textile manufacturer Alfred Stiassni. He, together with his wife Hermine and daughter Susanne, lived in the villa for only 9 years. The entire family fled the threatened occupation in 1938 to London and then to California via Brazil, where their descendants still live today.